Search programme

​Use the search function to search amongst programmes at Chalmers. The programme overview and the programme syllabus relating to your studies are generally from the academic year you began your studies.

​​​

Syllabus for

Academic year
KBB056 - Structural biochemistry
 
Owner: TKBIA
5,0 Credits (ECTS 7,5)
Grading: TH - Five, Four, Three, Not passed
Level: D
Department: 21 - CHEMISTRY AND CHEMICAL ENGINEERING


Teaching language: Swedish

Course module   Credit distribution   Examination dates
Sp1 Sp2 Sp3 Sp4 No Sp
0105 Examination 5,0 c Grading: TH   5,0 c   Contact examiner,  Contact examiner,  Contact examiner

In programs

TKMTA CHEMICAL ENGINEERING, Year 4 (elective)
TKMTL CHEMICAL ENGINEERING(FOR ENGINEERS WITH U.C.IN CHEMICAL ENG), Year 2 (elective)
TTFYA ENGINEERING PHYSICS, Year 4 (elective)
TKBIA BIOENGINEERING, Year 4 (elective)
TKEFA CHEMICAL ENGINEERING WITH ENGINEERING PHYSICS, Year 4 (elective)

Examiner:

Professor  Richard Neutze


Replaces

KBB055   Structural biochemistry


Eligibility:

For single subject courses within Chalmers programmes the same eligibility requirements apply, as to the programme(s) that the course is part of.

Course specific prerequisites

Anyone at fourth year within the Bt or K programmes at Chalmers will automatically be accepted. Students at fourth year in other programmes or at Gothenburg University will probably also be accepted, but must contact Richard Neutze in advance. The course will have a significant mathematical component.

Aim

This course aims to give an understanding of the major methods for structure determination of proteins. The course will cover X-ray crystallography and Nuclear Magnetic Resonance Spectroscopy in detail, & Electron Microscopy in less detail. The various tools needed to interpret structure etc. will also be covered.

Goal

See Aim.

Content

The course will consist of lectures and laboratory assignments. Lectures will run for two hours three times a week & will cover space groups; X-ray diffraction theory; NMR spectroscopy theory; Electron microscopy theory; and several examples of protein structures and methods. Inter-dispersed within the lecture course will be the occasional tutorial where specific problems will be worked through. Laboratory exercises will run for one afternoon over seven weeks and are compulsory. They will consist of X-ray crystallisation & data collection, model building & structure analysis, and NMR spectroscopy.

Literature

Lecture notes will be placed on the homepage http://www.csb.gu.se/neutze/structure/
A useful (but not compulsory) text is Principles of Protein X-ray Crystallography, Jan Drenth. A significant fraction of the X-ray diffraction theory will follow this book quite closely.

Examination

A written exam (80 %) plus tutorial & laboratory reports (20 %).


Page manager Published: Thu 03 Nov 2022.