Search programme

​Use the search function to search amongst programmes at Chalmers. The programme overview and the programme syllabus relating to your studies are generally from the academic year you began your studies.


Syllabus for

Academic year
KBB095 - Protein engineering
Owner: TKBIA
10,0 Credits (ECTS 15)
Grading: TH - Five, Four, Three, Not passed
Level: D

Teaching language: Swedish

Course module   Credit distribution   Examination dates
Sp1 Sp2 Sp3 Sp4 No Sp
0199 Examination 10,0 c Grading: TH   10,0 c   Contact examiner,  Contact examiner

In programs



Professor  Jan Rydström


For single subject courses within Chalmers programmes the same eligibility requirements apply, as to the programme(s) that the course is part of.


The course is designed to show how modern mole-cular and biochemical methods can be combined and used to specifically predict and test structure-function relations in proteins, a strategy commonly used in biomedical research and the biotechnology industry. This is achieved by selecting two model proteins, preferrably membrane proteins, presently bacterial cytochrome oxidase and transhydro-genase, as test proteins. A particular structure-function is addressed with either of the proteins, a mutagenesis protocol is designed, the mutant gene is sequenced, the mutant gene is expressed, and the recombinant protein is purified and characte-rized biochemically. All steps are carried out by the student, who therefore will learn and practice a number of useful methods in protein chemistry, and interpret mutagenesis information in terms of functional and structural consequences. The course includes a series of lectures in modern biotechnology given mostly by invited experts from e.g. the pharmaceutical industry, a literature task, presented in a manscript format as well as orally, and a study visit to a biomedical research institute or industry.


J.L. Cleland and C.S. Craik: Protein Engineering (Wiley -Liss, Inc., 1996).


Written exam.

Page manager Published: Thu 03 Nov 2022.