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Syllabus for

Academic year
TIF315 - Biological and biotechnical physics  
Biologisk och bioteknisk fysik
 
Syllabus adopted 2019-02-14 by Head of Programme (or corresponding)
Owner: MPPHS
7,5 Credits
Grading: TH - Five, Four, Three, Fail
Education cycle: Second-cycle
Major subject: Engineering Physics
Department: 16 - PHYSICS


Teaching language: English
Application code: 85123
Open for exchange students: Yes
Block schedule: B+

Module   Credit distribution   Examination dates
Sp1 Sp2 Sp3 Sp4 Summer course No Sp
0119 Examination 7,5c Grading: TH   7,5c   Contact examiner,  Contact examiner,  Contact examiner

In programs

MPPHS PHYSICS, MSC PROGR, Year 1 (compulsory elective)
MPBME BIOMEDICAL ENGINEERING, MSC PROGR, Year 2 (elective)

Examiner:

Fredrik Höök

  Go to Course Homepage


Eligibility:


In order to be eligible for a second cycle course the applicant needs to fulfil the general and specific entry requirements of the programme that owns the course. (If the second cycle course is owned by a first cycle programme, second cycle entry requirements apply.)
Exemption from the eligibility requirement: Applicants enrolled in a programme at Chalmers where the course is included in the study programme are exempted from fulfilling these requirements.

Course specific prerequisites

A basic understanding of thermodynamics, statistical physics and optics is advantageous

Aim

The course is aimed at providing the basic theoretical tools and an increased understanding of central concepts in biological and biotechnical physics. It will also provide an enhanced capability of planning, conducting, analyzing and presenting experimental with focus on medical diagnostics and drug development.

Learning outcomes (after completion of the course the student should be able to)

Understand and use key vocabulary and physical concepts of relevance for biological systems, and be able to describe the basic physical aspects of biological molecules, such as for example DNA, RNA, proteins, enzymes, cell membranes and live cells. Gain new insights about the structural complexity of live cells, exemplified using e.g. photosynthesis, the respiration chain and the function of our senses. Gain knowledge on how to plan and perform experiments in the subject, thereby gaining qualitative insight in some of the main concept of the course, with focus on biosensing and optical imaging.

Content

The theory part focuses on the following aspects: i) The molecules that are the functional building blocks of living organisms, ii) Physical models to describe life processes iii) Intermolecular interactions in chemical (non)equilibrium in the living cell, iv) Random walks and dynamical molecular machines, v) Biological membranes and transport into and out of cells, vi) Biological electricity, photosynthesis and the function of our senses.

An important aspect of the course is to utilize the tools and knowledge you have from before in thermodynamics, statistical physics, solid state physics and soft matter physics (or chemistry, biochemistry, physical chemistry if your background is not physics). The experimental part of the course consists of i) one introductory experiment in which you get used to handling buffers and biomolecules in experiments and ii) a larger project focusing on some of the fundamental concepts in the course, such the physical base for the intermolecular interactions that are utilized in e.g. medical diagnostics and how bioanalytical tools and different optical imaging systems are used in biotechnology and diagnostics.

An important aim with the experimental part is that you will get training of working in a wet-chemistry biological laboratory with biological molecules and solvents. The main experimental techniques that will be used are fluorescence microscopy, optical (UV-VIS), fluorescence spectroscopy and surface-sensitive tools. You will gain experience in planning and performing a biophysics experiment from the beginning to the end and to analyze and present the results in a written report and in an oral seminar.

Organisation

The course consists of around 12 lectures, focusing on theoretical models applicable to Biological Physics, and how the experimental methods used in the laboratory exercises and projects relate to the theory part, including additional applications of biological physics. It also included an experimental part consisting of both training experiments and a more challenging experimental project to be run at three occasions in groups of 3-4 students during the entire course

Literature

Kursbok: Physical Biology of the Cell, 2nd edition, Rob Phillips, Jane Kondev, Julie Theriot and Hernan Garcia; Garland Science 2013.

Examination including compulsory elements

Two to three home problems and two oral exams (one in group and one individual) covering the theory part. Written and oral presentation of the experimental project at the end of the course. The theoretical and experimental parts will have an equal weight in the final grade.


Published: Mon 28 Nov 2016.