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Graduate courses

Departments' graduate courses for PhD-students.

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Syllabus for

Academic year
KMG037 - Advanced molecular biology  
Avancerad molekylärbiologi
 
Syllabus adopted 2019-02-12 by Head of Programme (or corresponding)
Owner: MPBIO
7,5 Credits
Grading: TH - Five, Four, Three, Fail
Education cycle: Second-cycle
Major subject: Bioengineering
Department: 0114 - KEMI OCH MOLEKYLÄRBIOLOGI GU


Teaching language: English
Application code: 08116
Open for exchange students: No
Maximum participants: 20

Module   Credit distribution   Examination dates
Sp1 Sp2 Sp3 Sp4 Summer course No Sp
0114 Examination 7,5c Grading: TH   7,5c   Contact examiner,  Contact examiner   Contact examiner

In programs

MPBIO BIOTECHNOLOGY, MSC PROGR, Year 2 (elective)
MPCAS COMPLEX ADAPTIVE SYSTEMS, MSC PROGR, Year 2 (elective)

Examiner:

Julie Grantham

  Go to Course Homepage

Replaces

KMG036   Molecular biology 1


Eligibility:


In order to be eligible for a second cycle course the applicant needs to fulfil the general and specific entry requirements of the programme that owns the course. (If the second cycle course is owned by a first cycle programme, second cycle entry requirements apply.)
Exemption from the eligibility requirement: Applicants enrolled in a programme at Chalmers where the course is included in the study programme are exempted from fulfilling these requirements.

Course specific prerequisites

Undergraduate profile (BSc) with courses in cell and molecular biology, biochemistry, and applied microbiology.

Aim

This course shall focus on a detailed understanding of gene regulation and protein dynamics with particular emphasis on human diseases.

Learning outcomes (after completion of the course the student should be able to)

At the end of the course students should be able to:
  • Describe the dynamic behavior of the cytoskeleton and explain how this occurs
  • Explain the importance of protein quality control for cellular health
  • Describe the different families of molecular chaperones and their mechanisms of action
  • Describe how cancer cells are motile and explain the involvement of the cytoskeleton
  • Describe the cell biology of breast cancer
  • Describe the cell cycle and its regulation with focus on chromosome segregation and checkpoints
  • Describe the basic mechanisms for the major intracellular signaling pathways
  • Explain cellular regulation at the RNA level
  • Describe the role of oncogenes and tumor suppressor genes in cancer, the principles of cancer therapies and mechanisms of drug resistance
  • Describe the molecular process of meiotic cell division in mammals.
  • Describe the hierarchical molecular process and function of meiotic
    homologous recombination.
  • Describe how telomere length is maintained.
  • Describe how telomere is molecularly reconstituted during meiosis.

At the end of the lab classes students should be able to:

  • Carry out staining procedures for mammalian cells and identify normal and disrupted cytoskeletal structures.

Content

  • Eukaryotic cell cycle
  • Intracellular regulation
  • Cytoskeleton
  • Molecular chaperones
  • Cancer cell biology
  • Meosis
  • Telomere structure and function

Organisation

Lectures, laboratory classes (attendance is compulsory), seminars

Literature

No set book but Lodish et al., Molecular Cell biology or Alberts et al., Molecular Biology of the Cell would be useful. Recommended reading lists and handouts will be provided.

Examination including compulsory elements

Students must pass the written examination, complete the laboratory classes and laboratory reports.


Published: Wed 26 Feb 2020.