Masoumeh Dowlatshahi Pour: Brain stydy using mass spectrometry imaging technique

​We are what we eat. Diet can have strongly effect on the brain chemistry in specific on the lipid components which form  50-60% of the brain’s dry weight.Accordingly, as lipids are extensively involved in all cellular processes and tissue physiology, it is not surprising that abnormalities in lipid composition and distribution, and even the ratio of different lipids, are influenced by normal and abnormal biological functions.  Analytical tools based on lipidomics are being developed to facilitate investigations with high chemical sensitivity, specificity and spatial resolution to carry out studies at the massive complexity of biological system. In this regard,  mass spectrometry imaging can be used to determine and visualize the distribution of endogenous biological molecules such as lipids and peptides across biological materials, thus facilitating biological study. This technique provides both chemical information and the spatial organization of several different compounds, complex biomolecules and offers parallel detection of multiple analytes directly from biological samples without the need of target-specific reagents or radioactive or fluorescence labels which are common to use in other imaging techniques.
Category Popular Science Presentation
Lecturer Masoumeh Dowlatshahi Pour
Organizer Chalmers Library at Kuggen
Start 10/13/2017 8:15:00 AM
End 10/13/2017 8:45:00 AM
Location Chalmers Library Kuggen, Lindholmsplatsen 1
Campus Lindholmen